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What Causes Wound Healing?

There are three phases of wound healing: the inflammatory, fibroblastic, and maturation stages. If we take a simple laceration or cut inflammation begins after injury and the wound site swells as the biochemical ingredients needed for wound healing gather: leukocytes and monocytes fibrinogen, histamine, prostaglandins, and vasoactive substances. A great deal happens during this stage – it must occur to prepare the wound for the succeeding phases of wound healing. In fact, conventional drugs that limit inflammation such as non-steroidal anti-inflammatories (NSAID’s) will slow the healing of a wound! Next, fibroblasts begin to proliferate and position themselves for collagen synthesis. As collagen content increases, the wound site strengthens. The third and final stage of wound healing lasts the longest. This maturation, or remodeling phase, may continue for weeks or several years (depending on the severity of the injury), with gradual improvements in wound appearance.
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